UCLA college student Jonathan Moore (Anthony Edwards) is playing a game called "Gotcha" (popular on mid-1980s college campuses as "Assassin" or "Tag"), wherein the players are all assigned a mock "hit" on another player by use of a harmless paintball gun. Moore and his apartment roommate Manolo go on a vacation to Paris, France. After touring some of Paris, in a cafe Moore meets Sasha Banicek (Linda Fiorentino), a Czechoslovakian girl. Eventually, Jonathan has intercourse with Sasha, losing his virginity.
Jonathan decides to leave Manolo (who is heading to Spain) and go with Sasha to West Berlin to spend more time with her. Jonathan believes that he is in love with Sasha. There, Jonathan and Sasha continue to have sex and even go to an Oktoberfest beer gathering. One night, Sasha tells Jonathan that she has to go to East Berlin to pick up a package. One night after arriving in East Berlin, Sasha leaves their hotel room and walks to dark street corner. There, Sasha meets a German man who tells her the location of the pickup of her package. Meanwhile, Sasha was being monitored by a Soviet agent, who was sitting in a car at a distance. During the day, Sasha tells Jonathan that if she gives him a certain message, it means that he has to leave East Berlin immediately. At a cafe, Sasha gives Jonathan a package and says that a strudel is inside. A little later, Sasha tells Jonathan to meet her at the butcher shop near their hotel. All of a sudden, a Soviet agent begins to chase after Sasha. Sasha decides to use Jonathan (who is holding her package) to unknowingly get the package over to West Berlin. Meanwhile, Sasha is taken by the Soviet agent and East German secret police.
Jonathan goes to Checkpoint Charlie to cross the heavily fortified border into West Berlin. At the East German customs search, Jonathan is stripped of his clothes and given a cavity search. Meanwhile, Sasha is stripped and searched for possible espionage evidence. Vlad arrives at the border crossing to search for Jonathan, however Jonathan passes the border safely before he can be captured. Once in West Berlin, Jonathan feels liberated by the Westernized society. In the hotel, Jonathan receives a message from Sasha to meet him at a specified location. Jonathan finds out that his hotel room was broken into and robbed of his traveler's checks. Soviet agents eventually find Jonathan in West Berlin and chase him throughout a public park. Jonathan jumps into a water canal and manages to escape from the Soviets and stumbles upon a German rock group headed for Hamburg, who offer him a ride to the airport.
The rock group successfully get Jonathan to the airport (using full-face makeup to sneak him past a checkpoint) and Jonathan finally arrives in Los Angeles Tom Bradley International Airport and to his apartment. Soon, Vlad and a band of Soviet agents arrive too in Los Angeles. Once home, Jonathan stumbles upon a film canister, which was planted by Sasha. Jonathan visits his parents and tells them what happened in Germany but they cannot believe a word of it and think Jonathan is on drugs. Jonathan decides to call the FBI then the Central Intelligence Agency for help. Jonathan returns to find his apartment broken into and looted.
The CIA officer tells Jonathan to give them the photo film canister. At the Los Angeles headquarters of the CIA, Jonathan spots Sasha who looks like she was working there. Jonathan eventually meets up with Sasha. Sasha admits that she is Cheryl Brewster, a CIA agent, originally from Pittsburgh. Out of nowhere, Vlad and his gang begin to chase Jonathan and Cheryl on the UCLA campus. Jonathan eliminates all the Soviets with a tranquilizer gun which he gets from the campus veterinary sciences building. The Soviets are arrested, the CIA agents thank Jonathan for his (indirect) help in obtaining the film, and Sasha tells him she wants to continue their relationship.
After they part, Jonathan talks to a pretty student who rebuffs him coldly. As she walks away, he aims the tranquilizer pistol and shoots her in the rear.
#未删减版#
另外这部电影真的不恐怖，请放心食用，R级的程度也就只有个别画面比较血腥，与其说是恐怖片，为什么看到后面我觉得更像是动作片？还有，结局太过于突然了，警察局事件如何收场都没交代清楚，不管怎么说，强行爱与正义的收尾很不现实。
配乐还挺铅黄的，自己老婆的剧本差点意思，前半段不太行。
设定还是挺有想法的，之前也有足够的铺垫，气氛够吓人，就是不太明白这个后脑勺裂开是怎么操作的
看的是爱奇艺删减版。梅小时候是小天才演得，她演戏好模式化。
我的观影心理变化：本来以为是致命感应，然后发现是杀人直播，最后二十分钟才知道，原来是个寄生异形(字面上的)。
很杂糅，一个仿佛从斯蒂芬金《黑暗的另一半》里走出的恶魔，以温子仁东方怨灵的方式登场，加上一场武侠片式的打斗，效果居然还不差。另外，恶魔出场的bgm居然是《Where is my mind》的前奏。
设定完整自圆其说，后半段的视觉奇观到位，动作和造型都有创新，相当可以
悬疑属性大于恐怖属性，把这种奇幻拍成这样其实还是挺过瘾的，黑色幽默+温馨结尾很温子仁。显然更喜欢前面多一点，后面就变成了血浆盛宴，大屠杀那段有点《双瞳》的feel，没有条件的还是看未删减版本吧（笑）。PS：现在看后脑勺都有点...(3.5/5)
#未删减版#
如果是别人拍的，可以说还算满意，然而毕竟是温导的作品，又觉得他还不够用心。
预估成本4000万美元的《致命感应》已经不能算小成本恐怖片了，虽然肯定不是温导上心的项目和他最好的发挥，但也绝不踩雷。
还以为是某个 阴阳魔界 的0虚实莫辩0创意，事实上想多了。惊悚恐怖动作片3.5
寄生人被切掉了只剩下共享的一点脑子，能钻出来还带着牙齿和眼睛，钻回去头皮自动会缝合，能控制电流和无线电，like really？
各种元素缝合，CG依旧疲软……亮度一上去之后太多镜头露怯露的有点儿厉害。音乐很奇怪，个人不太能接受，music sup的工作做得不太好……恨奇艺你说你们这是在想啥呢……想开拓也别用R级恐怖片来啊……这不想不开么
3.5 真孤儿怨。揭开真相的那一刻，真是又变态又惊奇
难以形容温子仁脑子里都装着怎样令人震惊的一个个恐怖故事。
还是温子仁猛，这么老派的拍法竟然不显乏力，鬼屋+狂杀片爱好者将会得到双倍快乐。
这个反转就是换个花样的精神分裂，虽然剧情是在鬼扯，但也算是把老花样玩出了新意。最后监狱和警局的那两场杀人戏，难怪有人吐槽是刺客信条，不过确实拍得挺好看的。作为恐怖片我不推荐，但作为动作片我推荐。差点忘了温子仁也是个水平不错的动作片导演。
影片元素异常丰富，悬疑、动作、惊悚、恐怖、人格分裂、畸形……这种种的原料在温子仁手里，被非常和谐的封装在了一起。
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